The primary pharmacodynamic effect of Botulinum toxin type A is a chemical denervation of the treated muscle, resulting in a measurable decrease of the compound muscle action potential. This causes a localized reduction of muscle activity. When injected intramuscularly, the toxin induces paralysis of the affected muscle which temporarily reduces muscle activity.

Contraindications:

• Known hypersensitivity to any botulinum toxin products or to any of the excipients.
• Presence of infection at the proposed injection sites.
• Presence of myasthenia gravis, Eaton Lambert Syndrome or amyotrophic lateral sclerosis.

Store in a refrigerator at 2–8°C.

Keep vials in the outer carton in order to protect from light.

The post Relfydess Solution For Injection Single (100 units/ml) appeared first on Fox Pharma.

The post Dysport Single Vial (1 x 500IU vial) appeared first on Fox Pharma.

Mode of Action:

Clostridium botulinum neurotoxin type A blocks the peripheral release of the neurotransmitter acetylcholine at presynaptic cholinergic nerve terminals of neuromuscular junctions by cleaving SNAP-25, a protein integral to the successful docking and release of acetylcholine from vesicles situated within the nerve endings, thereby leading to denervation of the muscle and a flaccid paralysis.

Contraindications of Letybo:

-Hypersensitivity to the active substance or to any of the excipients.

-Generalised disorders of muscle activity such as myasthenia gravis, Lambert-Eaton syndrome, and amyotrophic lateral sclerosis

-Presence of acute infection or inflammation at the proposed injection sites.

Who Is the Ideal Patient For Letybo?

Ideal patients for Letybo would be adults under the age of 75 with concerns of deep to severe glabellar lines. However, practitioners should always do a full consultation with clients to determine whether the treatment is both suitable and beneficial for the patient.

Patients who are pregnant or breastfeeding should not use Letybo.

EMC: https://www.medicines.org.uk/emc/product/13707/smpc

Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.13707.pdf

Shop other toxins available at Fox Pharma here.

Fox Pharma are the official sub-distributors of Letybo in the UK

The post Letybo 50IU (Single Vial) appeared first on Fox Pharma.

The post Alluzience 125IU 2 Vials Twin Pack appeared first on Fox Pharma.

Treatment areas:

• Underarms in the treatment of hyperhidrosis

Mode of action:

It relaxes and limits the movement of muscles around the injection site as per other Clostridium botulinum type A toxins.

Contraindications:

• Known hypersensitivity to the active substance or to any of the excipients.
• Generalised disorders of muscle activity (e.g. myasthenia gravis, Lambert- Eaton syndrome) (as per other Clostridium botulinum type A toxins).
• Infection or inflammation at the proposed injection site (As per other Clostridium botulinum type A toxins).

Box contents:

1 Box (2 X 500IU Vials )

Store in a refrigerator at 2–8°C

Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.7261.pdf

The post Dysport 1 Box (2 X 500IU Vials ) appeared first on Fox Pharma.

• Prevents contractions of the facial muscles
• Creates a smoother-looking appearance
• Used to temporarily soften the appearance of facial wrinkles
• BOTOX may also be used in the treatment of severe hyperhidrosis

Treatment Areas:

• Moderate to severe vertical lines between the eyebrows (glabellar lines)
• Moderate to severe lateral canthal lines (crow’s feet lines)
• Moderate to severe forehead lines in adult patients
• Under the arms in the treatment of severe hyperhidrosis

Composition:

• This 50IU BOTOX vial contains clostridium botulinum type A neurotoxin complex, 0.5 milligrams of Albumin (Human), and 0.9 milligrams of sodium chloride

Box Contents:

• Box contains 1 x BOTOX 50IU vial
• Prescription-only medication

Contraindications of BOTOX:

• Known hypersensitivity to botulinum toxin type A or to any of the excipients
• Presence of infection at the proposed injection site(s)

Who Should Not Use BOTOX?

• Pregnant or lactating women
• Those with neurological or neuromuscular conditions
• Those in poor general health
• Those taking medications which could cause a reaction with BOTOX
• Those allergic to any of BOTOX’s ingredients, such as cow’s milk protein
• Those with very thick or sensitive skin
• Those with muscle weakness in the proposed injection site
• Those with a skin infection

Storage:

• Keep refrigerated at 2-8°C

Additional Information:

• EMC: https://www.medicines.org.uk/emc/product/859/smpc
• Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.859.pdf

The post BOTOX 50IU appeared first on Fox Pharma.

• Prevents contractions of the facial muscles
• Creates a smoother-looking appearance
• Used to temporarily soften the appearance of facial wrinkles
• BOTOX may also be used in the treatment of severe hyperhidrosis

Treatment Areas:

• Moderate to severe vertical lines between the eyebrows (glabellar lines)
• Moderate to severe lateral canthal lines (crow’s feet lines)
• Moderate to severe forehead lines in adult patients.
• Under the arms in the treatment of severe hyperhidrosis

*Please note, when treating primary hyperhidrosis of the axillae:

Medical history and physical examination, along with specific additional investigations as required, should be performed to exclude potential causes of secondary hyperhidrosis, such as hyperthyroidism and phaeochromocytoma. This will avoid symptomatic treatment of hyperhidrosis without the diagnosis and/or treatment of underlying disease.*

Composition:

•  Clostridium botulinum toxin type A, 200 units. Human serum albumin (EP) 0.5 mg. Sodium Chloride (USP) 0.5 mg 0.9 mg.

Box Contents:

• 1 x 200IU

Contraindications of Botox:

• Known hypersensitivity to botulinum toxin type A or to any of the excipients
• Presence of infection at the proposed injection site(s)

Who Should Not Use Botox?

• Those who are pregnant or breastfeeding
• Those who have a neurological disease
• Those allergic to cow’s milk protein.
• Those with neuromuscular disorders
• Those with poor general health
• Those with sensitive skin

Storage:

• Store in a refrigerator at 2–8°C

Additional Information:

EMC: https://www.medicines.org.uk/emc/product/859/smpc

Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.859.pdf

The post BOTOX 200IU appeared first on Fox Pharma.

• Prevents contractions of the facial muscles
• Creates a smoother-looking appearance
• Used to temporarily soften the appearance of facial wrinkles
• BOTOX may also be used in the treatment of severe hyperhidrosis

Treatment Areas:

• Moderate to severe vertical lines between the eyebrows (glabellar lines)
• Moderate to severe lateral canthal lines (crow’s feet lines)
• Moderate to severe forehead lines in adult patients
• Under the arms in the treatment of severe hyperhidrosis

Composition:

• This BOTOX 100IU vial contains clostridium botulinum type A neurotoxin complex, 0.5 milligrams of Albumin (Human), and 0.9 milligrams of sodium chloride

Box Contents:

• Box contains 1 x BOTOX 100IU vial
• Prescription-only medication

Contraindications of BOTOX:

• Known hypersensitivity to botulinum toxin type A or to any of the excipients
• Presence of infection at the proposed injection site(s)

Who Should Not Use BOTOX?

• Pregnant or lactating women
• Those with neurological or neuromuscular conditions
• Those in poor general health
• Those taking medications which could cause a reaction with BOTOX
• Those allergic to any of BOTOX’s ingredients, such as cow’s milk protein
• Those with very thick or sensitive skin
• Those with muscle weakness in the proposed injection site
• Those with a skin infection

Storage:

• Keep refrigerated at 2-8°C

Additional Information:

• EMC: https://www.medicines.org.uk/emc/product/859/smpc
• Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.859.pdf

The post BOTOX 100IU appeared first on Fox Pharma.

• Relaxes the muscles to prevent contractions
• Blocks transport of the neurotransmitter acetylcholine across the neuromuscular junction, located between the nerve end and the muscle fibre
• Used in the treatment of moderate to severe wrinkles in patients

Treatment Areas:

• Moderate to severe glabellar lines
• Lateral canthal lines (crow’s feet lines)

Composition:

•  Botulinum toxin type A, human albumin 200g/L and lactose monohydrate

Box Contents:

• Box contains a single Azzalure vial
• Prescription-only medication
• Indicated for use on moderate to severe Glabellar lines and Lateral canthal lines

Contraindications of Azzalure:

• Hypersensitivity to the active substance or any of the excipients
• Presence of infection at the proposed injection sites
• Presence of myasthenia gravis, Eaton Lambert Syndrome or amyotrophic lateral sclerosis

Who Should Not Use Azzalure?

• Pregnant and lactating women should not use this product as not enough clinical data has been collected to suggest that it is safe. There is a risk of this product passing through the mother to her baby
• Any individuals who develop hypersensitivity or an allergic reaction to the product should also refrain from using it. Children under 18 and adults over 65 should also not use this product
• Anyone with an infection on the skin surface at the proposed injection site should wait for the infection to completely disappear first
• If there is a probable muscle weakness (myasthenia gravis) already present, then do not use Azzalure either. The following diseases and conditions should also rule out the use of this medicine: Eaton Lambert syndrome and amyotrophic lateral sclerosis (degenerative nerve muscle disorder)

Storage:

• Keep refrigerated at 2-8°C

Additional Information:

• EMC: https://www.medicines.org.uk/emc/product/6584 
• Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.6584.pdf

The post Azzalure 125IU (Single Vial) appeared first on Fox Pharma.

Key Features:

• Contains: Sodium Chloride 0.9%, Benzyl Alcohol 0.9% and water for injection
• Mixing diluent

Summary:

• Contains: Sodium Chloride 0.9%, Benzyl Alcohol 0.9% and water for injection.
• Mixing diluent.

Contraindications:

• Do not use in pregnant or breastfeeding women.
• Do not use in patients with impaired kidney or liver function.
• Benzyl alcohol may cause allergic reactions.

Please note this is an UNLICENCED product and as such the prescriber takes full responsibility for prescribing the medicine and for overseeing the patient’s care, monitoring, and any follow up treatment.
An UNLICENCED product should only be used where a suitable LICENCED product does not exist.

The post TOR-BAC Bacteriostatic Sodium Chloride Ampoules Solution appeared first on Fox Pharma.